Description

This unique advanced textbook provides
a clear and comprehensive overview of
gene delivery, gene therapy and genetic
pharmacology, with descriptions of the main
gene transfer vectors and a set of selected
therapeutic applications, along with safety
considerations. The second edition features
new groundbreaking material on genome
editing using the recently discovered CRISPR/
Cas9 system and on cancer immunotherapy
by CAR-T cells. It also presents the historical
milestone of gene therapy application in the
field of severe combined immunodeficiency,
and other fields of gene therapy and molecular
medicine.
The use of gene transfer is exponentially
growing in the scientific and medical
communities for day-to-day cell biology
experiments and swift development of gene
therapy, which is already revolutionizing
medicine. In this advanced textbook, more
than 30 leading scientists come together to
explore these topics.
This educational introduction provides the
background material needed to further
explore the subject as well as relevant research
literature. It is an invaluable resource to
Master, PhD or MD students, post-doctoral
scientists or medical doctors, as well as any
scientist wishing to deliver a gene or synthetic
nucleotide or develop a gene therapy strategy.
The second edition?s simple and synthetic
content will be of value to any reader interested
in the biological and medical revolution
derived from the elucidation of the human
genome.