This is a book of real stories about the search for genomic spelling errors that have stark consequences: infants who pass away mysteriously, siblings with misplaced organs, a family with several instances of vision loss, sisters whose hearts fail in the prime of their youth, a boy whose blood can’t carry enough oxygen, a baby with cancer in the eye, a middle-aged patient battling cancer, and the author’s own color blindness. The search in each case proves to be a detective quest that connects the world of medical practice with that of molecular biology, traversing the world of computer algorithms along the way.
About the author Ramesh Hariharan is an Adjunct Professor at the Indian Institute of Science, and a Co-founder and Chief Technology Officer at Strand Life Sciences. The stories in this book come from first-hand experience analyzing genomes of patients.
